منابع مشابه
Identification of indoline-2-thione analogs as novel potent inhibitors of α-melanocyte stimulating hormone induced melanogenesis.
Based on the hits, 3,4-dihydroquinazoline-2-thione (1) and benzimidazole-2-thione (2), a series of indole-2-thione (3) and indole-2-thiol inhibitors (4) of melanogenesis were designed, synthesized and evaluated in melanoma B16 cells under the stimulant of α-melanocyte stimulating hormone (α-MSH). The indole-2-thione compounds (3a-g) exhibited an effective inhibitory activity on melanin synthesi...
متن کامل1,3-Dibenzylimidazolidine-2-thione
In the title compound, C(17)H(18)N(2)S, the imidazolidine ring adopts a twisted conformation. In the crystal, mol-ecules are linked by slipped π-π inter-actions between the benzene rings of neighbouring mol-ecules [centroid-to-centroid distance = 3.903 (2) Å].
متن کاملPerhydrobenzimidazole-2-thione
The studied crystal of the title compound, C(7)H(12)N(2)S, is a racemic mixture of two isomers, viz. S,S and R,R. The two isomers share the same position on a mirror plane in the space group P2(1)/m; thus all atoms except one are disordered between two positions in a 1:1 ratio. Inter-molecular N-H⋯S hydrogen bonds link the mol-ecules into chains propagating in the [010] direction.
متن کامل1H-Benzimidazole-2(3H)-thione
The asymmetric unit of the title compound, C(7)H(6)N(2)S, contains one half-mol-ecule; the C and S atoms of the C=S group lie on a crystallographic mirror plane. In the crystal structure, inter-molecular N-H⋯S hydrogen bonds link the mol-ecules.
متن کامل6-Methylpyridine-2(1H)-thione
There are two unique mol-ecules in the asymmetric unit of the title pyridine-thione derivative, C(6)H(7)NS, each of which adopts the thione rather than the mercaptan form. The rings in both mol-ecules are essentially planar, with maximum deviations from the least-squares planes through all non-H atoms of 0.021 (2) and 0.017 (2) Å. In the crystal structure, the mol-ecules form centrosymmetric cy...
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ژورنال
عنوان ژورنال: Journal of the Chilean Chemical Society
سال: 2005
ISSN: 0717-9707
DOI: 10.4067/s0717-97072005000200013